CGS 26303 is an endothelin-converting enzyme (ECE) inhibitor. CGS 26303 increases the expression of endothelin-converting enzyme-1 in endothelial cells. CGS 26303 attenuates cerebral vasospasm in a rabbit subarachnoid hemorrhage model. CGS 26303 improves birth survival and alleviates pulmonary hypoplasia in newborn rats in a rat model of congenital diaphragmatic hernia. CGS 26303 can be used for research on cardiovascular and cerebrovascular diseases and congenital diaphragmatic hernia[1][2][3].
Molecular Weight:
359.32
CAS Number:
[154116-31-1]
Formula:
C16H18N5O3P
Target:
Endothelin-Converting Enzyme (ECE)
Application Notes:
MCE Product type: Reference compound
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