AF-353 (Ro-4) is a potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist, with a pIC50 of 8.0 for both human and rat P2X3, and with a pIC50 of 7.3 for human P2X2/3[1][2].
Molecular Weight:
400.21
Purity:
99.53
CAS Number:
[865305-30-2]
Formula:
C14H17IN4O2
Target:
P2X Receptor
Application Notes:
Reference compound
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