SC209 (3-Aminophenyl Hemiasterlin) is a 3-aminophenyl hemiasterlin derivative that serves as a cytotoxin for ADCs, targeting tubulin. SC209 has reduced potential for drug efflux via P-glycoprotein 1 drug pump compared with other tubulin-targeting payloads. SC209 exhibits antitumor activity and can be used in the synthesis of ADC molecules[1][2].
Molecular Weight:
488.66
Purity:
99.52
CAS Number:
[1977557-86-0]
Formula:
C27H44N4O4
Target:
ADC Payload,Microtubule/Tubulin,P-glycoprotein
Application Notes:
ADC Related
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