FHT-1015 is a selective SMARCA4 (IC50 = 4 nM) and SMARCA2 (IC50 = 5 nM) (also known as BRG1 and BRM) inhibitor. FH-1015 is an allosteric inhibitor that causes conformation change in the BRG1/BRM protein upon interaction with an allosteric site, inhibiting ATPase activity. FH-1015 interferes with tumor cell growth and migration. FH-1015 can be studied in research for uveal melanoma and hematologic cancer[1][2][3][4].
Molecular Weight:
555.69
Purity:
98.41
CAS Number:
[2368903-18-6]
Formula:
C25H25N5O4S3
Target:
Epigenetic Reader Domain
Application Notes:
Reference compound
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