CDK4/6-IN-11 is a potent PROTAC CDK4/6 degrader[1]. CDK4/6-IN-11 consists of a thalidomide-based E3 ligase ligand (blue part) Thalidomide-NH-CH2-COOH (HY-131717), a target protein ligand (red part) Palbociclib (HY-50767), and a PROTAC linker (black part) Boc-NH-C4-Br (HY-W007803). E3 ligase ligand and linker can form Thalidomide-NH-amido-C4-Br (HY-170307).
Molecular Weight:
831.92
Purity:
98.07
CAS Number:
[2139329-47-6]
Formula:
C43H49N11O7
Target:
CDK,PROTACs
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted