LEB-03-146 is a WEE1 DUBTAC (deubiquitinase-targeting chimera) linking AZD1775 (Adavosertib) to the OTUB1 recruiter EN523 through a PEG2 linker. LEB-03-146 shows significant WEE1 stabilization in HEP3B hepatoma cancer cells[1].
Molecular Weight:
892.01
Purity:
98.08
CAS Number:
[2858812-91-4]
Formula:
C46H57N11O8
Target:
Wee1
Application Notes:
MCE Product type: Reference compound
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