20-HC-Me-Pyrrolidine (compound AI-3d) is a potent Aster protein inhibitor with IC50s of 0.11 µM, 0.06 µM, and 0.71 µM for Aster-A, Aster-B, and Aster-C, respectively. 20-HC-Me-Pyrrolidine blocks the ability of Asters to bind and transfer cholesterol. 20-HC-Me-Pyrrolidine also inhibits the movement of low-density lipoprotein (LDL) cholesterol to the endoplasmic reticulum (ER)[1].
Molecular Weight:
429.68
Purity:
99.69
Formula:
C28H47NO2
Target:
CETP,LDLR
Application Notes:
MCE Product type: Reference compound
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