SN-011 is a potent and selective mouse and human STING inhibitor, with an IC50 of 76 nM for STING signaling. SN-011 competes with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, blocking CDN binding and STING activation. SN-011 can be used for the research of STING-driven autoimmune and inflammatory disease[1].
Molecular Weight:
462.49
Purity:
99.94
CAS Number:
[2249435-90-1]
Formula:
C25H19FN2O4S
Target:
STING
Application Notes:
MCE Product type: Reference compound
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