Tuspetinib (hydrate), CAS [[2758339-04-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-145015A
Supplier Catalog Number:
HY-145015A
Alternative Catalog Number:
MCE-HY-145015A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
HM43239 (hydrate)
Tuspetinib (HM43239) hydrate is an orally active and selective FLT3 inhibitor with IC50s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. Tuspetinib hydrate inhibits the kinase activity of FLT3 as a reversible type I inhibitor and modulates p-STAT5, p-ERK, SYK, JAK1/2, and TAK1. Tuspetinib hydrate inhibits the proliferation and induces the apoptosis of leukemic cells[1][2][3].
Molecular Weight:
519.08
CAS Number:
[2758339-04-5]
Formula:
C29H35ClN6O
Target:
Apoptosis,FLT3
Application Notes:
MCE Product type: Reference compound
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