Tuspetinib (dihydrochloride), CAS [[3037216-20-6]] Preis auf Anfrage

Product Overview

• Article Name: Tuspetinib (dihydrochloride), CAS [[3037216-20-6]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-145015B
• Supplier Catalog Number: HY-145015B
• Alternative Catalog Number: MCE-HY-145015B-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: HM43239 (dihydrochloride)

Product Description

Tuspetinib (HM43239) dihydrochloride is an orally active and selective FLT3 inhibitor with IC50s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. Tuspetinib dihydrochloride inhibits the kinase activity of FLT3 as a reversible type I inhibitor and modulates p-STAT5, p-ERK, SYK, JAK1/2, and TAK1. Tuspetinib dihydrochloride inhibits the proliferation and induces the apoptosis of leukemic cells[1][2][3].

Product Properties

• Molecular Weight: 573.99
• CAS Number: [3037216-20-6]
• Formula: C29H35Cl3N6
• Target: Apoptosis,FLT3

Application Notes

• Application Notes: MCE Product type: Reference compound