SOS1-IN-5 is a potent inhibitor of SOS1. SOS1-IN-5 is a pyrimidobicyclic derivative. SOS1-IN-5 blocks the activation of KRAS by interfering with RAS-SOS1 interaction, and achieves the purpose of broad-spectrum inhibition of KRAS activity. SOS1-IN-5 has the potential for the research of cancer diseases (extracted from patent WO2021203768A1, compound 4)[1].
Molecular Weight:
536.54
CAS Number:
[2716956-47-5]
Formula:
C26H31F3N4O5
Target:
Ras,SOS1
Application Notes:
MCE Product type: Reference compound
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