ADAMTS-5-IN-3 (Example 37-2) is a potent inhibitor of ADAMTS-5 and ADAMTS-4 with IC50s of 8 and 12 nM, respectively. ADAMTS-5-IN-3 can be used for the research of diseases involving degradation of cartilage or disruption of cartilage homeostasis, in particular osteoarthrosis and/or rheumatoid arthritis[1].
Molecular Weight:
424.32
Purity:
98.89
CAS Number:
[2688733-96-0]
Formula:
C20H23Cl2N3O3
Target:
ADAMTS
Application Notes:
MCE Product type: Reference compound
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