NP3-146, CAS [[210826-47-4]] Preis auf Anfrage

Product Overview

• Article Name: NP3-146, CAS [[210826-47-4]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-145087
• Supplier Catalog Number: HY-145087
• Alternative Catalog Number: MCE-HY-145087-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: NLRP3-IN-5

Product Description

NP3-146 is a NLRP3 inflammasome inhibitor through locking the NACHT domain of NLRP3. NP3-146 shows potent inhibitory activity against IL-1beta release with an IC50 value of 0.171 µM in LPS (HY-D1056)/Nigericin (HY-127019)-stimulated BMDM cells. NP3-146 regulates the levels of cleaved Caspase-1 and cleaved IL-1beta in cell supernatants. NP3-146 can be used for the research of inflammatory diseases[1][2].

Product Properties

• Molecular Weight: 442.96
• CAS Number: [210826-47-4]
• Formula: C20H27ClN2O5S
• Target: Caspase,Interleukin Related,NOD-like Receptor (NLR)

Application Notes

• Application Notes: MCE Product type: Reference compound