S-777469 is a selective and orally available cannabinoid type 2 receptor (CB2) agonist with a Ki of 36 nM. S-777469 significantly suppresses compound 48/80-induced scratching behavior in mice in a dose-dependent manner. S-777469 produces its antipruritic effects by inhibiting itch signal transmission through CB2 agonism[1][2].
Molecular Weight:
414.47
Purity:
98.19
CAS Number:
[885496-53-7]
Formula:
C23H27FN2O4
Target:
Cannabinoid Receptor
Application Notes:
Reference compound
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