Aminopterin, CAS [[54-62-6]]

Product Overview

• Article Name: Aminopterin, CAS [[54-62-6]]
• Biozol Catalog Number: MCE-HY-14518
• Supplier Catalog Number: HY-14518
• Alternative Catalog Number: MCE-HY-14518-100MG, MCE-HY-14518-25MG, MCE-HY-14518-5MG, MCE-HY-14518-10MG, MCE-HY-14518-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: 4-Aminofolic acid, APGA

Product Description

Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a Ki of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia[1][2].

Product Properties

• Molecular Weight: 440.41
• Purity: 98
• CAS Number: [54-62-6]
• Formula: C19H20N8O5
• Target: Antifolate

Application Notes

• Application Notes: Reference compound