RTICBM-189 is a potent, brain-penetrant allosteric modulator of the cannabinoid type-1 (CB1) receptor with a pIC50 of 7.54 in Ca2+ mobilization assay. RTICBM-189 has pIC50s of 5.29 and 6.25 for hCB1 and mCB1, respectively. RTICBM-189 significantly and selectively attenuates the reinstatement of the addictive agent-seeking behavior in rats[1].
Molecular Weight:
309.19
Purity:
99.73
CAS Number:
[551909-15-0]
Formula:
C15H14Cl2N2O
Target:
Cannabinoid Receptor
Application Notes:
MCE Product type: Reference compound
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