IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 hydrochloride exhibits antitumor activies. Orally active[1].
Molecular Weight:
521.73
CAS Number:
[2310286-60-1]
Formula:
C16H19BrClFN8O4
Target:
Indoleamine 2,3-Dioxygenase (IDO)
Application Notes:
MCE Product type: Reference compound1
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