MS170 is a potent and selective PROTAC AKT degrader. MS170 depletes cellular total AKT (T-AKT) with the DC50 value of 32 nM. MS170 binds to AKT1, AKT2, and AKT3 with Kds of 1.3 nM, 77 nM, and 6.5 nM, respectively[1].
Molecular Weight:
870.44
Purity:
98.68
CAS Number:
[2376136-61-5]
Formula:
C45H56ClN9O7
Target:
Akt,PROTACs
Application Notes:
MCE Product type: Reference compound
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