PEG2000-C-DMG, a pegylated lipid, can be used for the preparation of Onpattro. Onpattro, a hepatically directed investigational RNAi therapeutic agent, harnesses this process to reduce the production of mutant and wild-type transthyretin by targeting the 3' untranslated region of transthyretin mRNA[1][2].
Molecular Weight:
2610.29
Purity:
99.97
CAS Number:
[1443687-74-8]
Formula:
C126H249NO52
Target:
Liposome
Application Notes:
MCE Product type: Oligonucleotides
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