Desmethyl bosentan is an active metabolite of the endothelin receptor antagonist bosentan (HY-A0013).1 Desmethyl bosentan (25 µM) activates the pregnane X receptor (PXR) in CV-1 monkey kidney cells expressing the human receptor in a reporter assay.
Molecular Weight:
537.59
CAS Number:
[253688-61-8]
Formula:
C26H27N5O6S
Target:
Cytochrome P450,Drug Metabolite
Application Notes:
MCE Product type: Reference compound
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