2-Deoxyguanosine 5-monophosphate (disodium hydrate), CAS [[146877-98-7]]
Biozol Catalog Number:
MCE-HY-145538
Supplier Catalog Number:
HY-145538
Alternative Catalog Number:
MCE-HY-145538-100MG,MCE-HY-145538-50MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
5-Deoxyguanylic acid (disodium hydrate)
2-Deoxyguanosine 5-monophosphate (5-Deoxyguanylic acid, dGMP) disodium hydrate is an oxidizable target of the photosensitizer pterin (PT) and can be used to evaluate the photosensitizing properties of biopterins (such as Bip, Fop and Cap) . Pterin causes a photosensitive reaction of dGMP under UV-A radiation, causing damage to DNA molecules. There are two main mechanisms for the photosensitive oxidation of purine nucleotides by pterin in vitro: one is the hydrogen abstraction reaction of electron transfer from dGMP to the triplet excited state of pterin (type I mechanism), and the other is the interaction between dGMP and pterin. The reaction produces singlet molecular oxygen (1O2) (Type II mechanism)[1][2].
Purity:
99
CAS Number:
[146877-98-7]
Formula:
C10H14N5O7P.xH2O.2Na
Target:
DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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