Mufemilast (Heymay005) is a selective and orally active phosphodiesterase 4 (PDE4) inhibitor (IC50 = 80-120 nM). Mufemilast modulates cytokines upregulated in Behsigmaets syndrome (BS). Mufemilast displays a significant inhibitory effect on TNF-alpha, which is an important proinflammatory cytokine target in the disease process of psoriasis. Mufemilast can be studied in research for diseases such as rheumatoid arthritis, psoriasis and BS[1][2][3][4][5].
Molecular Weight:
466.53
Purity:
99.67
CAS Number:
[1255909-03-5]
Formula:
C20H22N2O7S2
Target:
Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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