Onradivir (ZSP1273) is an orally active antiviral agent targeting influenza A virus RNA polymerase PB2 subunit with an IC50 of 0.562 nM. Onradivir inhibits cap binding to influenza A virus RNA polymerase PB2 subunit, suppresses viral replication, reduces viral titres and RNA loads, and inhibits influenza A virus infection. Onradivir maintains high survival rates in influenza A virus-infected mice, and reduces influenza A virus titers in a murine model. Onradivir can be used for the research of influenza A virus infection[1][2].
Molecular Weight:
440.45
Purity:
99.53
CAS Number:
[2200336-20-3]
Formula:
C22H22F2N6O2
Target:
DNA/RNA Synthesis,Influenza Virus
Application Notes:
MCE Product type: Reference compound
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