Zilurgisertib (INCB-000928, NBU-928) is a selective ALK2 inhibitor with an IC50 value of 15 nM. Zilurgisertib inhibits SMAD1/5 phosphorylation with an IC50 value of 63 nM. Zilurgisertib inhibits hepcidin production and improve anemia. Zilurgisertib can be used in melanoma research[1][2].
Molecular Weight:
502.65
Purity:
98.25
CAS Number:
[2173389-57-4]
Formula:
C30H38N4O3
Target:
TGF-beta Receptor
Application Notes:
Reference compound
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