Pozanicline, CAS [[161417-03-4]] Preis auf Anfrage

Catalog Number: MCE-HY-14565
Article Name: Pozanicline, CAS [[161417-03-4]] Preis auf Anfrage
Biozol Catalog Number: MCE-HY-14565
Supplier Catalog Number: HY-14565
Alternative Catalog Number: MCE-HY-14565-1UNIT
Manufacturer: MedchemExpress
Category: Biochemikalien
Alternative Names: ABT-089
Pozanicline (ABT-089) selectively activate neuronal nicotinic acetylcholine receptor (nAChR) subtypes, is a novel cholinergic agent that is a partial agonist at alpha4beta2* nAChRs (Ki=16 nM) and shows high selectivity for alpha6beta2* and alpha4alpha5beta2 nAChR subtypes, the binding affinity (Ki, rat) for Pozanicline to [3H] cytisine sites is 16.7 nM. Pozanicline reverses nicotine withdrawal-induced cognitive deficits, may be an effective component of novel therapeutic strategies for nicotine addiction[1].
Molecular Weight: 192.26
CAS Number: [161417-03-4]
Formula: C11H16N2O
Target: nAChR
Application Notes: Reference compound