GPR84 antagonist 2 (compound 33) is a potent, selective, and orally active GPR84 antagonist (IC50=8.95 nM). GPR84 antagonist 2 shows improved potency in the calcium mobilization assay and the ability to inhibit the chemotaxis of neutrophils and macrophages upon GPR84 activation. GPR84 antagonist 2 has the potential for the research of ulcerative colitis[1].
Molecular Weight:
605.42
Purity:
99.06
CAS Number:
[2244269-74-5]
Formula:
C28H16Cl2NaO4PS2
Target:
GPR84
Application Notes:
MCE Product type: Reference compound
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