E7820 (ER68203-00), an orally active aromatic sulfonamide derivative, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium. E7820 inhibits rat aorta angiogenesis with an IC50 of 0.11 µg/ml. E7820 modulates alpha-1, alpha-2, alpha-3, and alpha-5 integrin mRNA expression. Antiangiogenic and antitumor activity[1][2].
Molecular Weight:
336.37
Purity:
99.26
CAS Number:
[289483-69-8]
Formula:
C17H12N4O2S
Target:
Integrin,Molecular Glues
Application Notes:
MCE Product type: Reference compound
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