Mongersen (GED-0301) is a specific and orally active SMAD7 antisense oligonucleotide. Mongersen restores TGF-beta1 activity leading to inhibition of inflammatory signals. Mongersen can attenuate Crohns disease-like experimental colitis in mice[1][2].
Molecular Weight:
6604
Purity:
95.25
CAS Number:
[1443994-46-4]
Formula:
C200H241N69O107P20S20
Target:
TGF-beta/Smad
Application Notes:
MCE Product type: Oligonucleotides
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