Mongersen sodium is a specific and orally active SMAD7 antisense oligonucleotide. Mongersen sodium restores TGF-beta1 activity leading to inhibition of inflammatory signals. Mongersen sodium can attenuate Crohns disease-like experimental colitis in mice[1][2].
Molecular Weight:
6604 (free acid)
Purity:
99.61
CAS Number:
[1443994-98-6]
Formula:
C200H241N69O107P20S20Na20
Target:
TGF-beta/Smad
Application Notes:
MCE Product type: Oligonucleotides
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