Apatorsen (OGX-427) sodium is a 2-methoxyethyl-modified antisense oligonucleotide and also a Hsp27 inhibitor. Apatorsen sodium reduces Hsp27 mRNA and protein levels, impairs stress-induced cytoprotective functions, induces cell apoptosis, inhibits tumor growth and prevents metastasis. Apatorsen sodium is applicable to research related to non-small cell lung cancer, castration-resistant prostate cancer, breast cancer, ovarian cancer and bladder cancer[1][2].
Molecular Weight:
7157 (free acid)
Purity:
98.54
CAS Number:
[915443-09-3]
Formula:
C224H285N79Na19O116P19S19
Target:
HSP
Application Notes:
MCE Product type: Oligonucleotides
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