MAX-40279 (hemiadipate), CAS [[2388506-44-1]]

Product Overview

• Article Name: MAX-40279 (hemiadipate), CAS [[2388506-44-1]]
• Biozol Catalog Number: MCE-HY-145723C
• Supplier Catalog Number: HY-145723C
• Alternative Catalog Number: MCE-HY-145723C-10MG,MCE-HY-145723C-10MMX1ML,MCE-HY-145723C-100MG,MCE-HY-145723C-25MG,MCE-HY-145723C-5MG,MCE-HY-145723C-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

MAX-40279 hemiadipate is a dual and orally active inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hemiadipate is also effective against the FLT3 mutants such as FLT3D835Y, suggesting that it can overcome resistance to Quizartinib (HY-13001) and Sorafenib (HY-10201). MAX-40279 hemiadipate inhibits NDRG1 phosphorylation at Ser330 and suppresses endothelial-to-mesenchymal transition (EndMT). MAX-40279 hemiadipate can be used for the research of acute myelogenous leukemia (AML)[1][2][3].

Product Properties

• Molecular Weight: 584.66
• Purity: 99.26
• CAS Number: [2388506-44-1]
• Formula: C22H23FN6OS.1/2C6H10O4
• Target: FGFR,FLT3

Application Notes

• Application Notes: MCE Product type: Reference compound