Danvatirsen, CAS [[1402357-06-5]]

Product Overview

• Article Name: Danvatirsen, CAS [[1402357-06-5]]
• Biozol Catalog Number: MCE-HY-145729
• Supplier Catalog Number: HY-145729
• Alternative Catalog Number: MCE-HY-145729-1MG,MCE-HY-145729-5MG,MCE-HY-145729-10MG,MCE-HY-145729-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: AZD9150

Product Description

Danvatirsen (AZD9150) is an antisense oligonucleotide targeting STAT3. Danvatirsen reduces the viability and promotes apoptosis of leukemia cell lines. Danvatirsen inhibits the expression of endogenous STAT3 and its downstream target genes, and reduces the proliferation and tumorigenicity of neuroblastoma and lymphoma cells. Danvatirsen inhibits tumor growth rate in mouse models of neuroblastoma, lymphoma and non-small cell lung cancer. Danvatirsen achieves STAT3 mRNA and protein depletion in a mouse model of epidermoid carcinoma. Danvatirsen can be used in research related to lymphoma, myelodysplastic syndrome, acute myeloid leukemia, neuroblastoma and non-small cell lung cancer[1][2][3][4].

Product Properties

• Molecular Weight: 5422.00
• Purity: 99.12
• CAS Number: [1402357-06-5]
• Formula: C172H217N56O88P15S15
• Target: Apoptosis,STAT

Application Notes

• Application Notes: MCE Product type: Oligonucleotides