beta-Glucuronide-dPBD-PEG5-NH2, CAS [[2246363-68-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-145736
Supplier Catalog Number:
HY-145736
Alternative Catalog Number:
MCE-HY-145736-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
beta-Glucuronide-dPBD-PEG5-NH2 is the beta-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD. beta-glucuronide-linkage as a cleavable linker. beta-Glucuronide-dPBD-PEG5-NH2, as a proagent of cIRCR201-dPBD, reduces side effects. beta-Glucuronide-dPBD-PEG5-NH2 can induce apoptosis and arrest cell cycle. beta-Glucuronide-dPBD-PEG5-NH2 has antitumor activity[1].
Molecular Weight:
1696.66
CAS Number:
[2246363-68-6]
Formula:
C78H101N7O35
Target:
Apoptosis,Drug-Linker Conjugates for ADC
Application Notes:
MCE Product type: ADC Related
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