beta-Glucuronide-dPBD-PEG5-NH2 (TFA), CAS [[2246364-63-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-145736A
Supplier Catalog Number:
HY-145736A
Alternative Catalog Number:
MCE-HY-145736A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
beta-Glucuronide-dPBD-PEG5-NH2 TFA is the beta-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD.beta-glucuronide-linkage as a cleavable linker. beta-Glucuronide-dPBD-PEG5-NH2 TFA, as a proagent of cIRCR201-dPBD, reduces side effects. beta-Glucuronide-dPBD-PEG5-NH2 TFA can induce apoptosis and arrest cell cycle. beta-Glucuronide-dPBD-PEG5-NH2 TFA has antitumor activity[1].
Molecular Weight:
1810.69
CAS Number:
[2246364-63-4]
Formula:
C80H102F3N7O37
Target:
Apoptosis,Drug-Linker Conjugates for ADC
Application Notes:
MCE Product type: ADC Related
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