AGI-41998, CAS [[2377492-26-5]]

Product Overview

• Article Name: AGI-41998, CAS [[2377492-26-5]]
• Biozol Catalog Number: MCE-HY-145778
• Supplier Catalog Number: HY-145778
• Alternative Catalog Number: MCE-HY-145778-10MG,MCE-HY-145778-10MMX1ML,MCE-HY-145778-50MG,MCE-HY-145778-5MG,MCE-HY-145778-100MG,MCE-HY-145778-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

AGI-41998 is a potent and orally active inhibitor of methionine adenosyltransferase 2A (MAT2A) that effectively penetrates the blood-brain barrier. AGI-41998 exhibits inhibitory activities against MAT2A and S-adenosyl methionine (SAM) in HCT-116 MTAP-null cells with IC50s of 22 nM and 34 nM. AGI-41998 can significantly inhibit the proliferation of HCT-116 cells and tumor growth. AGI-41998 can be used to study the role of SAM regulation in the central nervous system (CNS) and colon cancer[1].

Product Properties

• Molecular Weight: 505.29
• Purity: 99.94
• CAS Number: [2377492-26-5]
• Formula: C22H16BrF3N4O2
• Target: Methionine Adenosyltransferase (MAT)

Application Notes

• Application Notes: MCE Product type: Reference compound