JPS014 TFA is a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimeras (PROTAC). JPS014 TFA degrades class I histone deacetylase (HDAC). JPS014 TFA is potent HDAC1/2 degrader correlated with greater total differentially expressed genes and enhanced apoptosis in HCT116 cells[1].
Molecular Weight:
968.09
Purity:
98.40
Formula:
C48H60F3N7O9S
Target:
Apoptosis,HDAC,PROTACs
Application Notes:
MCE Product type: Reference compound
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