Top/HDAC-IN-1, CAS [[2775446-49-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-145851
Supplier Catalog Number:
HY-145851
Alternative Catalog Number:
MCE-HY-145851-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Top/HDAC-IN-1 (Compound 29b) is a topoisomerase/HDAC dual inhibitor with IC50s of 18, 230, 790, 87, and 5250 nM for HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8, respectively. Top/HDAC-IN-1 exhibits potent antitumor activities against the HCT116 cell line with the IC50 of 180 nM. Top/HDAC-IN-1 efficiently induces apoptosis with G2 cell cycle arrest in HCT116 cells[1].
Molecular Weight:
509.56
CAS Number:
[2775446-49-4]
Formula:
C29H27N5O4
Target:
Apoptosis,HDAC,Topoisomerase
Application Notes:
MCE Product type: Reference compound1
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