J-1063 is a potent, selective and orally active ALK5 inhibitor with an IC50 of 0.039 µM. J-1063 shows anti-fibrotic effect by the inhibition of inflammatory infiltration, collagen deposition, and hepatocytes necrosis. J-1063 has the potential for the research of liver fibrosis[1].
Molecular Weight:
425.51
CAS Number:
[2374772-46-8]
Formula:
C24H19N5OS
Target:
TGF-beta Receptor
Application Notes:
MCE Product type: Reference compound1
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