Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity[1][2]. Lopinavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 14.2 µM[3].
Molecular Weight:
628.80
Purity:
99.97
CAS Number:
[192725-17-0]
Formula:
C37H48N4O5
Target:
HIV,HIV Protease,SARS-CoV
Application Notes:
MCE Product type: Reference compound
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