TLR7/8 agonist 6 is a TLR7/8 agonist with EC50s of 0.18 µM and 5.34 µM in TLR7 or TLR8 HEK-SEAP reporter cells, respectively. TLR7/8 agonist 6 potently stimulates production of TNFalpha, IFNgamma, and IL-1beta. TLR7/8 agonist 6 can be used for research on cancer and infectious diseases[1].