TLR7/8 Antagonist 1 (Compound 16c) is the potent antagonist of TLR7/8 with IC50s of 3.91 and 2.19 µM, respectively. TLR7/8 Antagonist 1 is an imidazoquinoline derivative compound. Toll-like receptors (TLRs) 7 and 8 are key targets in the development of immunomodulatory drugs for researching infectious disease, cancer, and autoimmune disorders[1].
Molecular Weight:
417.50
CAS Number:
[2901020-63-9]
Formula:
C24H27N5O2
Target:
Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Reference compound
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