PKN1/2-IN-1 is a potent cell permeabilizer and selective PKN1/2 inhibitor with IC50 values of 16 nM and 210 nM for PKN1 and PKN2, respectively, and Ki values of 8 nM and 108 nM, respectively. PKN1/2-IN-1 exhibits strong intracellular PKN2 binding capacity in NanoBRET assays (IC50 = 2.1 µM). PKN1/2-IN-1 can be used to study physiological processes such as tumor cell migration[1].
Molecular Weight:
241.29
Purity:
99.92
CAS Number:
[942425-34-5]
Formula:
C14H15N3O
Target:
PKC
Application Notes:
MCE Product type: Reference compound
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