MRTX-EX185, CAS [[2621927-57-7]] Preis auf Anfrage

Product Overview

• Article Name: MRTX-EX185, CAS [[2621927-57-7]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-145962
• Supplier Catalog Number: HY-145962
• Alternative Catalog Number: MCE-HY-145962-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

MRTX-EX185 is a potent KRAS (G12D) inhibitor with an IC50 of 90 nM. MRTX-EX185 can binds both GDP-loaded and active GNP states of KRAS and KRAS (G12D). MRTX-EX185 exhibits broad-spectrum binding properties with IC50s of 110, 290, 130 and 240 nM for KRAS WT, KRAS (G12C), KRAS (Q61H), KRAS (G13D). MRTX-EX185 also binds GDP-loaded HRAS. MRTX-EX185 can be used to study various RAS-driven tumors (such as pancreatic cancer) [1].

Product Properties

• Molecular Weight: 564.65
• CAS Number: [2621927-57-7]
• Formula: C33H33FN6O2
• Target: Ras

Application Notes

• Application Notes: MCE Product type: Reference compound