3OMe-m7GpppAmpG (Tris) is a trinucleotide Cap1 analog with the structure m7 (3OMeG)(5) ppp (5)(2OMeA) pG, and also functions as a cis-acting ligase ribozyme inhibitor. 3OMe-m7GpppAmpG (Tris) effectively reduces free 5-triphosphate groups on RNA transcripts, thereby enabling efficient co-transcriptional capping of in vitro transcribed mRNA. 3OMe-m7GpppAmpG (Tris) is not only widely used in the preparation of modified mRNA including trivalent influenza vaccine candidates, but also applicable to studies related to SARS-CoV-2 infection and other relevant research[1][2][3][4].
Molecular Weight:
1523.10
Formula:
C45H78N18O33P4
Target:
Nucleoside Antimetabolite/Analog,SARS-CoV
Application Notes:
MCE Product type: Oligonucleotides
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