m7GpppAmpG (m7G(5)ppp(5)(2OMeA)pG) is a trinucleotide 5' end cap analog. m7GpppAmpG binds to eIF4E with a KD value of 45.6 nM. m7GpppAmpG caps RNA with a capping efficiency of 90%. m7GpppAmpG enhances mRNA stability and translation efficiency. m7GpppAmpG is used in mRNA therapeutic research[1][2][3].