3,3-Difluorobenzaldazine (DFB) is a selective positive allosteric modulator of mGluR5. 3,3-Difluorobenzaldazine potentiates 3- to 6-fold action for mGlu5 agonists (Glutamate, Quisqualate, and 3,5-Dihydroxyphenylglycine), with EC50s in the 2 to 5 µM range[1].
Molecular Weight:
244.24
Purity:
99.44
CAS Number:
[15332-10-2]
Formula:
C14H10F2N2
Target:
mGluR
Application Notes:
MCE Product type: Reference compound
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