EGFR-IN-57, CAS [[2492382-37-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-146138
Supplier Catalog Number:
HY-146138
Alternative Catalog Number:
MCE-HY-146138-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
EGFR-IN-57 (Compound 25a) is a potent, orally active EGFR-TK inhibitor with an IC50 of 0.054 µM. EGFR-IN-57 also inhibits VEGFR-2, CK2alpha, topoisomerase IIbeta and tubulin polymerization with IC50 values of 0.087, 0.171, 0.13 and 3.61 µM, respectively. EGFR-IN-57 induces cell cycle arrest at G2/M and pre-G1 phases. EGFR-IN-57 induces cancer cell apoptosis[1].
