Necrostatin 2 is a potent necroptosis inhibitor. EC50 for inhibition of necroptosis in FADD-deficient Jurkat T cells treated with TNF-alpha is 0.05 µM. Necrostatin 2 is also a RIPK1 inhibitor.
Molecular Weight:
277.71
Purity:
99.92
CAS Number:
[852391-19-6]
Formula:
C13H12ClN3O2
Target:
RIP kinase
Application Notes:
MCE Product type: Reference compound
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