BET-IN-8 (Compound 27) is a potent inhibitor of BET with a Ki and Kd of 0.83 and 0.571 µM, respectively. BET-IN-8 ameliorates LPS-induced sepsis in vivo. BET-IN-8 has the potential for the research of sepsis[1].
Molecular Weight:
423.48
CAS Number:
[2769893-19-6]
Formula:
C22H21N3O4S
Target:
Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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