PARP1/2/TNKS1/2-IN-1 (Compound I-9) is a dual PARP-1, PARP-2, TNKS1 and TNKS2 inhibitor with IC50 values of 0.25 nM, 1.2 nM, 13.5 nM and 4.15 nM against PARP-1, PARP-2, TNKS1 and TNKS2, respectively. PARP1/2/TNKS1/2-IN-1 exhibits favorable synergistic antitumor efficacy and induces apoptosis[1].
Molecular Weight:
634.66
Purity:
98.66
CAS Number:
[2243453-32-7]
Formula:
C35H31FN6O5
Target:
Apoptosis,PARP
Application Notes:
MCE Product type: Reference compound
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